Is High Intensity Exercise Sabotaging Your Weights

Why Some People Experience Adverse Effects While Others Don't:

The Role of Genes and Neuroscience in Personal Wellness

Have you ever wondered why certain substances or activities affect some people drastically while others seem unaffected? From psychosis triggered by THC to weight gain despite exercise, the way our bodies respond to various stimuli is deeply personal—and it’s rooted in our unique genetic makeup and neurobiological factors. These differences aren’t just random; they stem from how our genes, brain chemicals, and hormonal biomarkers interact with the environment and visa versa.

Weed: Why It Leads to Serious Mental Illness For Some, But Not All

While some people can consume THC (the active compound in cannabis) without significant issues, others may experience intense paranoia or even psychosis. This reaction is influenced by the quality and volume of THC, as well as genetic factors related to dopamine regulation, methylation, autophagy, and other biological functions, which vary greatly among individuals.

Some people may have genetic variations that make their brain more sensitive to THC, leading to adverse effects like anxiety, hallucinations, or cognitive impairments. Understanding your genetic predisposition can help you make more informed choices, ensuring your wellness stays in check.

Why Some People Develop Alcohol Use Disorder (AUD) and Others Don’t

For some, consuming alcohol seems like a harmless activity, while others may quickly develop a problematic relationship with it. This difference is often due to genetic predispositions related to alcohol metabolism and neurobiological pathways that affect addiction.

Variations in genes like ADH1B and ALDH2 impact how quickly alcohol is processed in the body, influencing how rewarding or addictive alcohol feels.

Moreover, some individuals’ brains may respond more intensely to the pleasurable effects of alcohol, making it easier to develop alcohol use disorder (AUD). A personalized approach to wellness—including testing your genes and neuroscience biomarkers—can help you understand your unique risk factors for addiction and guide you toward healthier choices.

High-Intensity Interval Training: Beneficial for Some, Detrimental for Others

High Intensity Interval training (HIIT) has become a go-to fitness trend, but for some people, it can actually be detrimental to their physical and mental well-being.

For individuals with certain genetic variants related to inflammation, recovery, or cortisol regulation, high-intensity exercise may increase the risk of injury, burnout, or mental fatigue. In these cases, a more moderate exercise regimen might be more effective and sustainable.

The key is knowing your body's genetic makeup and neuroscience biomarkers, which can indicate how your body responds to stress, exercise, and recovery.

Weight Gain and Difficulty Losing Weight: The Genetic and Neurobiological Factors

It’s a common frustration: you eat healthy, exercise regularly, but still struggle to lose weight—or you find yourself gaining weight without explanation. This can be due to a variety of genetic factors that influence metabolism, fat storage, and hunger regulation.

For instance, some people have genetic variations that slow down their metabolism or make them more likely to store fat rather than burn it. Additionally, neurobiological factors like leptin resistance (which impacts hunger cues) or cortisol dysregulation (which is linked to stress-related weight gain) may be at play.

By testing your genetic and neuroscience biomarkers, you can understand what’s truly affecting your ability to lose weight, and make targeted adjustments to your diet, exercise, and stress management techniques.

The Power of Personalized Wellness: Test, Optimize, Thrive

At Wired BioHealth, we offer clinical-grade tests to measure your genetic and neuroscience biomarkers, identifying factors that affect your physical and mental wellness, like mood swings, focus issues, or weight challenges. We don’t just provide the results—we also give personalized recommendations and review them one-on-one with you, helping you make informed choices to optimize your health.

Personalized wellness moves beyond a “one-size-fits-all” approach, allowing you to tailor fitness, stress management, and nutrition to your unique biology.

Take control of your health—contact us today to learn more and schedule your consultation.

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